(3-Bromo-4-fluorophenyl)acetic acid

(3-Bromo-4-fluorophenyl)acetic acid - Names and Identifiers

Name	3-Bromo-4-fluorophenylacetic Acid
Synonyms	QV1R DF CE 3-BROMO-4-FLUOROPHENYLACETIC ACID 3-Bromo-4-fluorophenylacetic acid 3-Bromo-4-fluorophenylacetic Acid 3-Bromo-4-fluorobenzeneacetic acid (3-Bromo-4-fluorophenyl)acetic acid Benzeneacetic acid, 3-bromo-4-fluoro- 2-(3-bromo-4-fluorophenyl)acetic acid 3-BROMO-4-FLUOROPHENYLACETIC ACID(RS20013039)
CAS	194019-11-9
InChI	InChI=1/C8H6BrFO2/c9-6-3-5(4-8(11)12)1-2-7(6)10/h1-3H,4H2,(H,11,12)

(3-Bromo-4-fluorophenyl)acetic acid - Physico-chemical Properties

Molecular Formula	C8H6BrFO2
Molar Mass	233.03
Density	1.697±0.06 g/cm3(Predicted)
Melting Point	67 °C
Boling Point	326.8±27.0 °C(Predicted)
Flash Point	151.4°C
Water Solubility	Slightly soluble in water.
Vapor Presure	8.55E-05mmHg at 25°C
Appearance	Powder
pKa	4.09±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.57
MDL	MFCD04038373

(3-Bromo-4-fluorophenyl)acetic acid - Risk and Safety

Hazard Class

IRRITANT

(3-Bromo-4-fluorophenyl)acetic acid - Introduction

Acid, chemical formula C8H6BrFO2, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
Acid is a colorless to yellow crystalline solid with a special odor. It has a melting point of 62-65 degrees Celsius and a boiling point of 293 degrees Celsius. It is insoluble in water, but soluble in organic solvents such as ethanol and ether. It is a flammable substance that can burn at high temperatures, open flames or in the presence of oxygen.

Use:
Acid has certain uses in drug synthesis and biochemical research. It can be used as an intermediate in organic synthesis for the synthesis of other compounds, such as drugs, dyes and pesticides. In addition, it can also be used for the Study of substitution reactions on organic compounds.

Method:
It can be prepared by reacting 3-fluoro-4-methoxyphenylacetic Acid with bromine. First, in the presence of chlorinated antimonic acid, 3-fluoro-4-methoxyphenylacetic acid is reacted with bromine to generate 3-bromo-4-methoxyphenylacetic acid, and then through the addition of alkaline environment, at 120 degrees Celsius, the methoxy group is replaced with bromine to obtain Acid.

Safety Information:
Acid is an organic compound, and attention should be paid to its protective measures. It is an irritating substance that may cause inflammation when in contact with the skin and eyes. Wear appropriate protective gloves, glasses and masks during operation. In addition, it is a flammable substance and should be kept away from fire and high temperatures. During storage and use, attention should be paid to fire and explosion prevention measures and good ventilation conditions should be maintained. Any work involving this compound should be carried out in a safe laboratory environment and following proper laboratory procedures.

Last Update：2024-04-09 21:01:54